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Palmitoyl serinol
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Catalog No. T60957Cas No. 126127-31-9
Alias N-Palmitoyl serinol
Palmitoyl serinol (N-Palmitoyl serinol), an analog of the endogenous cannabinoid N-palmitoylethanolamine, significantly stimulated an IL-4-mediated decrease in cellular ceramide levels in human epidermal keratinocytes (KC). Palmitoyl serinol stimulates the production of specific ceramide species and neurotransmitters through an endogenous cannabinoid receptor CB1-dependent mechanism. production of specific ceramide species as well as the total amount of ceramide.
Palmitoyl serinol
😃Good
Catalog No. T60957Alias N-Palmitoyl serinolCas No. 126127-31-9
Palmitoyl serinol (N-Palmitoyl serinol), an analog of the endogenous cannabinoid N-palmitoylethanolamine, significantly stimulated an IL-4-mediated decrease in cellular ceramide levels in human epidermal keratinocytes (KC). Palmitoyl serinol stimulates the production of specific ceramide species and neurotransmitters through an endogenous cannabinoid receptor CB1-dependent mechanism. production of specific ceramide species as well as the total amount of ceramide.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | 93 € | 35 days | |
| 10 mg | 185 € | 35 days | |
| 50 mg | 748 € | 35 days | |
| 100 mg | 1.330 € | 35 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Palmitoyl serinol (N-Palmitoyl serinol), an analog of the endogenous cannabinoid N-palmitoylethanolamine, significantly stimulated an IL-4-mediated decrease in cellular ceramide levels in human epidermal keratinocytes (KC). Palmitoyl serinol stimulates the production of specific ceramide species and neurotransmitters through an endogenous cannabinoid receptor CB1-dependent mechanism. production of specific ceramide species as well as the total amount of ceramide. |
| In vitro | Palmitoyl serinol promotes ceramide production through a CB1-dependent mechanism in an in vitro model of skin inflammation. [1] |
| Alias | N-Palmitoyl serinol |
| Molecular Weight | 329.52 |
| Formula | C19H39NO3 |
| Cas No. | 126127-31-9 |
| Smiles | O=C(NC(CO)CO)CCCCCCCCCCCCCCC |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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