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PARP1-IN-33 (Example 6) is a PARP1 inhibitor with an IC50 of 0.41 nM. It demonstrates protective effects on retinal cells, exhibiting an EC50 of 0.02 nM in inhibiting hydrogen peroxide-induced MTS activity in human retinal pigment epithelial cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | Inquiry | 10-14 weeks | |
50 mg | Inquiry | 10-14 weeks |
Description | PARP1-IN-33 (Example 6) is a PARP1 inhibitor with an IC50 of 0.41 nM. It demonstrates protective effects on retinal cells, exhibiting an EC50 of 0.02 nM in inhibiting hydrogen peroxide-induced MTS activity in human retinal pigment epithelial cells. |
Targets&IC50 | PARP1:0.41 nM |
In vitro | PARP1-IN-33 exhibits strong protective effects against damage to retinal cells caused by hydrogen peroxide. |
Molecular Weight | 426.91 |
Formula | C23H24ClFN4O |
Cas No. | 2640677-68-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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