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PARP1-IN-17 is an inhibitor that targets PARP-1 (IC50=19.24 nM ) with a slightly reduced affinity for PARP-2 (IC50=32.58 nM ) and induces apoptosis. It exhibits robust anti-proliferative activity [1].
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Description | PARP1-IN-17 is an inhibitor that targets PARP-1 (IC50=19.24 nM ) with a slightly reduced affinity for PARP-2 (IC50=32.58 nM ) and induces apoptosis. It exhibits robust anti-proliferative activity [1]. |
In vitro | PARP1-IN-17 (Compound 11b) demonstrates antiproliferative effects on A549, OVCAR-3, HCT-116, and MCF-7 cells after 72 hours of exposure [1]. |
Storage | Shipping with blue ice. |
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