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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | $45 | In Stock | |
500 mg | $119 | In Stock |
Description | PEG3-methylamine is a PEG-based PROTAC linker that can be used to synthesize PROTAC molecules. |
In vitro | The PROTAC molecule itself contains three different parts: a ligand that binds to the target protein, a ligand that binds to the E3 ligase, and a linker that connects the two ligands. Its mechanism of action is: after binding to the target protein, the PROTAC molecule brings the target protein and the E3 ligase together, allowing E3 to ubiquitinate and mark the target protein, and the ubiquitinated target protein can be degraded through the proteasome pathway.[1] |
Molecular Weight | 163.22 |
Formula | C7H17NO3 |
Cas No. | 282551-10-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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