Shopping Cart
- Remove All
Your shopping cart is currently empty
Argentina
Australia
Austria
Belgium
Brazil
Bulgaria
Croatia
Cyprus
Czech
Denmark
Egypt
Estonia
Finland
France
Germany
Greece
Hong Kong
Hungary
Iceland
India
Ireland
Israel
Italy
Korea
Latvia
Lebanon
Malaysia
Malta
Morocco
Netherlands
New Zealand
Norway
Poland
Portugal
Romania
Singapore
Slovakia
Slovenia
Spain
Sweden
Switzerland
Taiwan,China
Thailand
Turkey
United Kingdom
United States
Other Countries
Select your Country or Region
PNU288034
Contact us for more batch information
PNU288034
Catalog No. T12512Cas No. 383199-88-0
PNU288034 is a potent oxazolidinone antibiotic with antimicrobial activity for the prevention and treatment of Gramnegative infections.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $700 | Backorder | |
| 5 mg | $1,800 | Backorder |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "PNU288034"
(+)-Magnoflorine iodide
T3S13204277-43-4
(+)-Magnoflorine iodide (Thalictrine iodide) has anti-inflammatory activity, it can inhibit inflammations.
- $41
Size
QTY
Quinoxyfen
T20672124495-18-7
Quinoxyfen has antimicrobial activity and can be used to study powdery mildew.
- $30
Size
QTY
Kasugamycin hydrochloride
T276219408-46-9
Kasugamycin hydrochloride (Kasumin) is an aminoglycoside antibiotic that was originally isolated in 1965, from Streptomyces kasugaensis, a Streptomyces strain found near the Kasuga shrine in Nara, Japan. Kasugamycin hydrochloride was discovered by Hamao Umezawa, who also discovered kanamycin and bleomycin, as a drug which could prevent growth of a fungus causing rice blast disease.
- $22
Size
QTY
Mycophenolic acid
Cited
T133524280-93-1
Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.
- $40
Size
QTY
CitedCedryl acetate
T295677-54-3
Cedryl acetate (Cedranyl acetate) , an acetylated from cedarwood oil, has been applied to chemistry for its properties as a chiral and cell signaling reagent with antifungal and immunotoxicity functions.
- $29
Size
QTY
Colutehydroquinone
TN1521181311-16-0
Colutehydroquinone is an antifungal isoflavonoid from Colutea arborescens.
- $105
Size
QTY
Antibacterial compound 2
T11427170104-58-2
Antibacterial compound 2 is a potent antimicrobial agent effective against many human veterinary pathogens, inhibiting multi-drug resistant staphylococci, enterococci and streptococci, as well as anaerobic bacteria.
- $700
Size
QTY
Snail/HDAC-IN-1
T632602415281-52-4
Snail/HDAC-IN-1 is a Snail/HDAC inhibitor agent with antimicrobial and anticancer activity, reduces Snail protein expression, induces apoptosis, and can be used in the study of solid tumors.
- $92
Size
QTY
Toyocamycin
T17143606-58-6
Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM). Toyocamycin induces apoptosis.
- $39
Size
QTY
Broxaldine
T42183684-46-6
Broxaldine (Brobenzoxaldine) is a small molecular drug with antiprotozoal activity.
- $30
Size
QTY
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | PNU288034 is a potent oxazolidinone antibiotic with antimicrobial activity for the prevention and treatment of Gramnegative infections. |
| In vitro | In vitro studies, conducted to characterize the involved transporters, demonstrate uptake of PNU-288034 by human organic anion transporter 3 (OAT3; Km = 44 +/- 5 μM) and human multidrug and toxin extrusion protein 1 (hMATE1; Km = 340 +/- 55 μM)[1]. |
| In vivo | In liver microsomes across species, PNU-288034 exhibits metabolic stability, and the unchanged drug is cleared in the urine through an apparent active renal secretion process in rat and monkey. Coadministration of PNU-288034 with the OAT3 inhibitor probenecid significantly increases the plasma area under the curve (170%) and reduces both plasma and renal clearance in monkey. Furthermore, coadministration of PNU-288034 with cimetidine also reduces plasma clearance in rats to a rate comparable to probenecid coadministration[1]. |
| Molecular Weight | 403.4 |
| Formula | C16H19F2N3O5S |
| Cas No. | 383199-88-0 |
| Storage | store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。 Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Dose Conversion
You can also refer to dose conversion for different animals. More
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.