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KT-474
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Catalog No. T74411Cas No. 2432994-31-3
Alias PROTAC IRAK4 degrader-7, KYM-001, KYM001, KT474
KT-474 (KYM-001) is a PROTAC degrader targeting interleukin-1 receptor-associated kinase 4 (IRAK4) with antitumor activity for the study of autoimmune, inflammatory, and cardiovascular disease disorders.
KT-474
😃Good
Catalog No. T74411Alias PROTAC IRAK4 degrader-7, KYM-001, KYM001, KT474Cas No. 2432994-31-3
KT-474 (KYM-001) is a PROTAC degrader targeting interleukin-1 receptor-associated kinase 4 (IRAK4) with antitumor activity for the study of autoimmune, inflammatory, and cardiovascular disease disorders.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $247 | In Stock | |
| 5 mg | $629 | 7-10 days | |
| 10 mg | $886 | 7-10 days | |
| 25 mg | $1,290 | 7-10 days | |
| 50 mg | $1,770 | 7-10 days | |
| 100 mg | $2,390 | 7-10 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | KT-474 (KYM-001) is a PROTAC degrader targeting interleukin-1 receptor-associated kinase 4 (IRAK4) with antitumor activity for the study of autoimmune, inflammatory, and cardiovascular disease disorders. |
| Alias | PROTAC IRAK4 degrader-7, KYM-001, KYM001, KT474 |
| Molecular Weight | 865.93 |
| Formula | C44H49F2N11O6 |
| Cas No. | 2432994-31-3 |
| Smiles | O=C1N(C=2C(=C(C#CCOC3CCN(C[C@H]4CC[C@@H](CC4)N5C=C(NC(=O)C6=C7N(N=C6)C=CC(=N7)N8[C@@]9(C[C@](C8)(OC9)[H])[H])C(C(F)F)=N5)CC3)C=CC2)N1C)C%10C(=O)NC(=O)CC%10 |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (92.39 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
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