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PROTAC SMARCA2 degrader-15
😃Good
Catalog No. T200440Cas No. 2568276-78-6
SMARCA2 degrader-4 (compound I-332) is a PROTAC-based degrader targeting the SMARCA2 protein, exhibiting a DC50 value of less than 100 nM in A549 cells and achieving a maximum degradation rate (Dmax%) of over 90% after a 24-hour treatment period.
PROTAC SMARCA2 degrader-15
😃Good
Catalog No. T200440Cas No. 2568276-78-6
SMARCA2 degrader-4 (compound I-332) is a PROTAC-based degrader targeting the SMARCA2 protein, exhibiting a DC50 value of less than 100 nM in A549 cells and achieving a maximum degradation rate (Dmax%) of over 90% after a 24-hour treatment period.
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Product Introduction
Bioactivity
Chemical Properties
| Description | SMARCA2 degrader-4 (compound I-332) is a PROTAC-based degrader targeting the SMARCA2 protein, exhibiting a DC50 value of less than 100 nM in A549 cells and achieving a maximum degradation rate (Dmax%) of over 90% after a 24-hour treatment period. |
| Molecular Weight | 928.16 |
| Formula | C50H61N11O5S |
| Cas No. | 2568276-78-6 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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