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Protease-Activated Receptor-1, PAR-1 Agonist acetate

Catalog No. T38836L

Protease-Activated Receptor-1, PAR-1 Agonist acetate is a selective proteinase-activated receptor1 (PAR-1) agonist peptide. Protease-Activated Receptor-1, PAR-1 Agonist acetate corresponds to PAR1 tethered ligand and which can selectively mimic theactions of thrombin via this receptor[1][2].

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Protease-Activated Receptor-1, PAR-1 Agonist acetate, CAS N/A

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

In vitro

Protease-Activated Receptor-1, PAR-1 Agonist acetate induces activation of protein kinase C isoenzymes alpha and epsilon in human HT-29 colon carcinoma cells expressing PAR1 endogeneously. On the cellular level, Protease-Activated Receptor-1, PAR-1 Agonist acetate and thrombin prompted HT-29 cell migration and matrix adhesion by a PKCepsilon-dependent mechanism as concluded because of the inhibition of PAR1-mediated effects by the PKC inhibitor bisindolylmaleimide I and the PKCepsilon translocation inhibitory peptide EAVSLKPT but not by the PKC inhibitor G? 6976[2].

Molecular Weight	822.95
Formula	C37H62N10O11

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Related Products

Related compounds with same targets

SLIGRL-NH2 TRAP-6 PAR-4 Agonist Peptide, amide acetate PAR-4 Agonist Peptide, amide TFLLR-NH2 Thrombin Receptor Activator for Peptide 5 (TRAP-5) Protease-Activated Receptor-4 AC-264613

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Protease-Activated Receptor-1, PAR-1 Agonist acetate GPCR/G Protein Protease-activated Receptor ProteaseActivated Receptor1, PAR1 Agonist acetate Protease Activated Receptor 1, PAR 1 Agonist acetate Inhibitor inhibitor inhibit

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