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Resolvin D2 (RvD2) is a potent TRPV1 inhibitor and pro-absorptive mediator with anti-inflammatory, anti-infective and pro-absorptive effects for the study of immune disorders and cancer.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 μg | $383 | 35 days | |
25 μg | $886 | 35 days | |
50 μg | $1,710 | 35 days | |
100 μg | $2,990 | 35 days |
Description | Resolvin D2 (RvD2) is a potent TRPV1 inhibitor and pro-absorptive mediator with anti-inflammatory, anti-infective and pro-absorptive effects for the study of immune disorders and cancer. |
Targets&IC50 | TRPV1:0.1 nM, TRPA1:2 nM |
In vitro | Resolvin D2 is a potent inhibitor of TRPV1 (IC50 = 0.1 nM) and TRPA1 (IC50 = 2 nM) in primary sensory neurons. It may be ideal for the treatment of periapical lesions by promoting positive regression of inflammation and regeneration of pulp-like tissue following root canal infection. Resolvin D2 also reduces leukocyte-endothelial cell interactions in vivo through endothelium-dependent nitric oxide production and direct modulation of leukocyte adhesion receptor expression. [1][2] |
In vivo | Peripheral injection of Resolvin D2 (10 ng; plantar injection) has potent inhibitory effects on inflammatory pain. [3] |
Alias | Rv-D2, RvD2 |
Molecular Weight | 376.49 |
Formula | C22H32O5 |
Cas No. | 810668-37-2 |
Smiles | [C@H]([C@H](C/C=C\CC)O)(/C=C/C=C/C=C\C=C\[C@H](C/C=C\CCC(O)=O)O)O |
Relative Density. | 1.101 g/cm3 (Predicted) |
Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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