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Resolvin D2

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Catalog No. T12707Cas No. 810668-37-2
Alias Rv-D2, RvD2

Resolvin D2 (RvD2) is a potent TRPV1 inhibitor and pro-absorptive mediator with anti-inflammatory, anti-infective and pro-absorptive effects for the study of immune disorders and cancer.

Resolvin D2

Resolvin D2

😃Good
Catalog No. T12707Alias Rv-D2, RvD2Cas No. 810668-37-2
Resolvin D2 (RvD2) is a potent TRPV1 inhibitor and pro-absorptive mediator with anti-inflammatory, anti-infective and pro-absorptive effects for the study of immune disorders and cancer.
Pack SizePriceAvailabilityQuantity
10 μg$38335 days
25 μg$88635 days
50 μg$1,71035 days
100 μg$2,99035 days
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Concentration:0.1 mg/mL
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Product Introduction

Bioactivity
Description
Resolvin D2 (RvD2) is a potent TRPV1 inhibitor and pro-absorptive mediator with anti-inflammatory, anti-infective and pro-absorptive effects for the study of immune disorders and cancer.
Targets&IC50
TRPV1:0.1 nM, TRPA1:2 nM
In vitro
Resolvin D2 is a potent inhibitor of TRPV1 (IC50 = 0.1 nM) and TRPA1 (IC50 = 2 nM) in primary sensory neurons. It may be ideal for the treatment of periapical lesions by promoting positive regression of inflammation and regeneration of pulp-like tissue following root canal infection.
Resolvin D2 also reduces leukocyte-endothelial cell interactions in vivo through endothelium-dependent nitric oxide production and direct modulation of leukocyte adhesion receptor expression. [1][2]
In vivo
Peripheral injection of Resolvin D2 (10 ng; plantar injection) has potent inhibitory effects on inflammatory pain. [3]
AliasRv-D2, RvD2
Chemical Properties
Molecular Weight376.49
FormulaC22H32O5
Cas No.810668-37-2
Smiles[C@H]([C@H](C/C=C\CC)O)(/C=C/C=C/C=C\C=C\[C@H](C/C=C\CCC(O)=O)O)O
Relative Density.1.101 g/cm3 (Predicted)
Storage & Solubility Information
Storagestore at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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