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Retinoic acid-d5
😃Good
Catalog No. T67921Cas No. 78996-15-3
Alias Vitamin A acid-d5, ATRA-d5, all-trans-Retinoic acid-d5, Accutane-d5
Retinoic acid-d5 (Vitamin A acid-d5) is the deuterium-labeled form of Retinoic acid. Retinoic acid is a natural RAR receptor agonist with an IC50 of 14 nM for RARα/β/γ and a Kd of 17 nM for PPARβ/δ. Retinoic acid, a metabolite of vitamin A, plays an important role in cell growth, differentiation and organ development. Retinoic acid acts by activating retinoic acid receptor alpha as an inhibitor of the transcription factor Nrf2.
Retinoic acid-d5
😃Good
Catalog No. T67921Alias Vitamin A acid-d5, ATRA-d5, all-trans-Retinoic acid-d5, Accutane-d5Cas No. 78996-15-3
Retinoic acid-d5 (Vitamin A acid-d5) is the deuterium-labeled form of Retinoic acid. Retinoic acid is a natural RAR receptor agonist with an IC50 of 14 nM for RARα/β/γ and a Kd of 17 nM for PPARβ/δ. Retinoic acid, a metabolite of vitamin A, plays an important role in cell growth, differentiation and organ development. Retinoic acid acts by activating retinoic acid receptor alpha as an inhibitor of the transcription factor Nrf2.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $1,200 | 35 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Retinoic acid-d5 (Vitamin A acid-d5) is the deuterium-labeled form of Retinoic acid. Retinoic acid is a natural RAR receptor agonist with an IC50 of 14 nM for RARα/β/γ and a Kd of 17 nM for PPARβ/δ. Retinoic acid, a metabolite of vitamin A, plays an important role in cell growth, differentiation and organ development. Retinoic acid acts by activating retinoic acid receptor alpha as an inhibitor of the transcription factor Nrf2. |
| Alias | Vitamin A acid-d5, ATRA-d5, all-trans-Retinoic acid-d5, Accutane-d5 |
| Molecular Weight | 305.47 |
| Formula | C20H28O2 |
| Cas No. | 78996-15-3 |
| Smiles | C(=CC(=CC=CC(=CC(O)=O)C)C)C=1C(C)(C)CCC(C1C([2H])([2H])[2H])([2H])[2H] |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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