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Tartrazine

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Purity:98.82%

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COA HPLC HNMR

Tartrazine

Catalog No. TN2258Cas No. 1934-21-0

Tartrazine (Acid Yellow 23) is a food additive that belongs to a class of artificial dyes and contains an azo group; it has significant genotoxic effect , may be harmful to health and its prolonged use could trigger carcinogenesis.

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Pack Size	Price	Availability
500 mg	$42	In Stock
1 g	$50	In Stock
1 mL x 10 mM (in DMSO)	$46	In Stock

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Product Introduction

Bioactivity

Description	Tartrazine (Acid Yellow 23) is a food additive that belongs to a class of artificial dyes and contains an azo group; it has significant genotoxic effect , may be harmful to health and its prolonged use could trigger carcinogenesis.
In vitro	We assessed the cytotoxicity of Tartrazine by 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide test and the response of DNA repair through comet assay (alkaline version). We used different concentrations of the dye, ranging from 0.25-64.0 mM. The results demonstrated that Tartrazine has no cytotoxic effects. However, this dye had a significant genotoxic effect at all concentrations tested. Although most of the damage was amenable to repair, some damage remained higher than positive control after 24 h of repair[2]
Alias	FD&C Yellow No. 5, Acid Yellow 23

Chemical Properties

Molecular Weight	534.36
Formula	C16H9N4Na3O9S2
Cas No.	1934-21-0

Storage & Solubility Information

Storage

keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 40 mg/mL (74.86 mM)

H2O: 45 mg/mL (84.21 mM)

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	1.8714 mL	9.3570 mL	18.7140 mL	93.5699 mL
5 mM	0.3743 mL	1.8714 mL	3.7428 mL	18.7140 mL
10 mM	0.1871 mL	0.9357 mL	1.8714 mL	9.3570 mL
20 mM	0.0936 mL	0.4678 mL	0.9357 mL	4.6785 mL
50 mM	0.0374 mL	0.1871 mL	0.3743 mL	1.8714 mL

H2O

	1mg	5mg	10mg	50mg
100 mM	0.0187 mL	0.0936 mL	0.1871 mL	0.9357 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Tech Support

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