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Teclistamab
😃Good
Catalog No. T76881Cas No. 2119595-80-9
Alias JNJ-64007957, JNJ64007957
Teclistamab (JNJ-64007957) is a human bispecific monoclonal antibody targeting the CD3 receptor expressed on the surface of t-cells and the b-cell maturation antigen (BCMA) expressed on the surface of malignant multiple myeloma b-lineage cells for the treatment of relapsed and refractory multiple myeloma.
Teclistamab
Teclistamab
😃Good
Purity: 95%
Catalog No. T76881Alias JNJ-64007957, JNJ64007957Cas No. 2119595-80-9
Teclistamab (JNJ-64007957) is a human bispecific monoclonal antibody targeting the CD3 receptor expressed on the surface of t-cells and the b-cell maturation antigen (BCMA) expressed on the surface of malignant multiple myeloma b-lineage cells for the treatment of relapsed and refractory multiple myeloma.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $689 | In Stock | |
| 5 mg | $1,590 | In Stock | |
| 10 mg | $2,180 | In Stock | |
| 25 mg | $3,230 | In Stock | |
| 50 mg | $4,370 | 8-10 weeks | |
| 100 mg | $5,890 | 8-10 weeks |
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Concentration:13.11 mg/mL
Purity:95%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Teclistamab (JNJ-64007957) is a human bispecific monoclonal antibody targeting the CD3 receptor expressed on the surface of t-cells and the b-cell maturation antigen (BCMA) expressed on the surface of malignant multiple myeloma b-lineage cells for the treatment of relapsed and refractory multiple myeloma. |
| In vitro | Methods: Frozen BM MNCs were treated with Teclistamab (0-532 nM) with or without exogenous healthy T cells to measure target engagement and killing. Results: Teclistamab-induced cytotoxicity in BM MNCs had comparable EC50s (1.5-4.2 nM) in all 3 patient samples; Teclistamab-mediated T cell activation was also similar in all BM MNC samples with EC50s (0.93 - 1.75 nM). [1] |
| Alias | JNJ-64007957, JNJ64007957 |
| Cas No. | 2119595-80-9 |
Storage & Solubility Information
| Storage | store at low temperature | store at -80°C | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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