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TRPV3 antagonist 74a

Catalog No. T37429Cas No. 1432051-63-2
Alias TRPV3 74a

TRPV3 antagonist 74a (TRPV3 74a) is a specific TRPV3 antagonist for the study of neurological disorders.

TRPV3 antagonist 74a

TRPV3 antagonist 74a

Catalog No. T37429Alias TRPV3 74aCas No. 1432051-63-2
TRPV3 antagonist 74a (TRPV3 74a) is a specific TRPV3 antagonist for the study of neurological disorders.
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1 mg$499In Stock
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Purity:≥98.0%
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Product Introduction

Bioactivity
Description
TRPV3 antagonist 74a (TRPV3 74a) is a specific TRPV3 antagonist for the study of neurological disorders.
In vivo
In WT mice, TRPV3 antagonist 74a (150 μg; Intradermal injection; 30 minutes) significantly reduced the number of scratches[2].
AliasTRPV3 74a
Chemical Properties
Molecular Weight338.32
FormulaC17H17F3N2O2
Cas No.1432051-63-2
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 1 mg/mL (2.96 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9558 mL14.7789 mL29.5578 mL147.7891 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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