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TT-012 has anti-tumor activity, selectively binds dynamic MITF and disrupts the dimer formation and DNA binding of the latter. TT-012 can inhibit the transcription of MITF in B16F10 melanoma cells. TT-012 inhibited the growth and metastasis of MITF melanoma cells in animal models. TT-012 is less cytotoxic to liver and immune cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $38 | In Stock | |
5 mg | $89 | In Stock | |
10 mg | $147 | In Stock | |
25 mg | $297 | In Stock | |
50 mg | $488 | In Stock | |
100 mg | $788 | In Stock | |
500 mg | $1,590 | In Stock |
Description | TT-012 has anti-tumor activity, selectively binds dynamic MITF and disrupts the dimer formation and DNA binding of the latter. TT-012 can inhibit the transcription of MITF in B16F10 melanoma cells. TT-012 inhibited the growth and metastasis of MITF melanoma cells in animal models. TT-012 is less cytotoxic to liver and immune cells. |
Molecular Weight | 349.34 |
Formula | C19H15N3O4 |
Cas No. | 1164471-33-3 |
Smiles | N(C(/C=C/C1=CC=CO1)=O)C=2N=C(NC(/C=C/C3=CC=CO3)=O)C=CC2 |
Relative Density. | 1.385 g/cm3 (Predicted) |
Storage | store at low temperature | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 100 mg/mL (286.25 mM), Sonication is recommended. ![]() H2O: < 1 mg/mL (insoluble or slightly soluble) ![]() | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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