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TX2-120-1 possesses the ability to bind with Her3, exhibiting an IC50 of 56 nM for Her3. It can be utilized in the synthesis of TX2-121-1.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | Inquiry | 10-14 weeks | |
50 mg | Inquiry | 10-14 weeks |
Description | TX2-120-1 possesses the ability to bind with Her3, exhibiting an IC50 of 56 nM for Her3. It can be utilized in the synthesis of TX2-121-1. |
In vivo | TX2-120-1 (0.5-2 μM; 12 h) is less effective in inducing Her3 degradation or blocking Her3-dependent signaling in PC9 GR4 cells due to the absence of a hydrophobic adamantyl group. |
Molecular Weight | 469.54 |
Formula | C26H27N7O2 |
Cas No. | 1603845-45-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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