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Virodhamine

Virodhamine
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Virodhamine

Catalog No. T64371Cas No. 287937-12-6
Virodhamine (O-arachidonoyl ethanolamine), an endocannabinoid, is an antagonist of CB1 receptor and an agonist of CB2 receptor. Virodhamine can be used for the research of neurological disorders such as Alzheimer's diseases.
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Pack SizePriceAvailabilityQuantity
2 mg$485 days
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Product Introduction

Bioactivity
Description
Virodhamine (O-arachidonoyl ethanolamine), an endocannabinoid, is an antagonist of CB1 receptor and an agonist of CB2 receptor. Virodhamine can be used for the research of neurological disorders such as Alzheimer's diseases.
In vitro
virodhamine (50nM, 72h) treatment augmented features associated with megakaryocytic development: cells increased adherence and membrane expansion. virodhamine (10, 20, 40 µM, 72h) treatment increases the expression of CD61[1].
In vivo
Virodhamine (1, 5, 10 mg/kg; i.p. once) repairs the nicotine (0.8 mg/kg) and immobilization stress induced anxiety in Male ICR mice[2].
AliasO-arachidonoyl ethanolamine
Chemical Properties
Molecular Weight347.53
FormulaC22H37NO2
Cas No.287937-12-6
Storage & Solubility Information
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 90mg/mL (259mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.8774 mL14.3872 mL28.7745 mL143.8725 mL
5 mM0.5755 mL2.8774 mL5.7549 mL28.7745 mL
10 mM0.2877 mL1.4387 mL2.8774 mL14.3872 mL
20 mM0.1439 mL0.7194 mL1.4387 mL7.1936 mL
50 mM0.0575 mL0.2877 mL0.5755 mL2.8774 mL
100 mM0.0288 mL0.1439 mL0.2877 mL1.4387 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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