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ZXH-1-161

Name: ZXH-1-161
Brand: TargetMol
SKU: T63010
Rating: 4.5 (1 reviews)

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Catalog No. T63010Cas No. 2407654-51-5

ZXH-1-161 is a potent regulator of cereblon (CRBN) with an IC50 of 39 μM in wild-type MM1.S cells, selectively degrading GSPT1, and is useful for studying multiple myeloma.

ZXH-1-161

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Purity: 99.01%

Catalog No. T63010Cas No. 2407654-51-5

ZXH-1-161 is a potent regulator of cereblon (CRBN) with an IC50 of 39 μM in wild-type MM1.S cells, selectively degrading GSPT1, and is useful for studying multiple myeloma.

Pack Size	Price	Availability	Quantity
100 mg	$1,490	6-8 weeks

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Purity:99.01%

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COA

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description

ZXH-1-161 is a potent regulator of cereblon (CRBN) with an IC50 of 39 μM in wild-type MM1.S cells, selectively degrading GSPT1, and is useful for studying multiple myeloma.

Chemical Properties

Molecular Weight	468.51
Formula	C₂₆H₂₄N₆O₃
Cas No.	2407654-51-5
Smiles	N(C1=C2C(C(=O)N(C2)C3C(=O)NC(=O)CC3)=CC=C1)C4=NC(NC=5C=C6C(=CC5)CCC6)=NC=C4

Storage & Solubility Information

Storage

store at low temperature | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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