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Lenalidomide-Br
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Lenalidomide-Br
Catalog No. T18064Cas No. 2093387-36-9
Lenalidomide-Br is an analog of the cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, which is used in the recruitment of CRBN proteins. It is able to utilize linkers to attach to protein ligands to form PROTACs such as the PROTAC STAT3 degrader SD-36.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 mg | $30 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $30 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Lenalidomide-Br is an analog of the cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, which is used in the recruitment of CRBN proteins. It is able to utilize linkers to attach to protein ligands to form PROTACs such as the PROTAC STAT3 degrader SD-36. |
| In vitro | Lenalidomide-Br can be conjugated to a protein ligand via a linker, forming PROTACs that induce the ubiquitination-mediated degradation of oncogenic proteins. |
| In vivo | Lenalidomide-Br can form a PROTAC by coupling with a protein's ligand. PROTAC acts as an inducer of ubiquitin-mediated degradation of oncogenic proteins [1][2]. |
| Molecular Weight | 323.14 |
| Formula | C13H11BrN2O3 |
| Cas No. | 2093387-36-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 30 mg/mL (92.84 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
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