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Lysophosphatidylcholine 18:2

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Catalog No. T36791Cas No. 22252-07-9
Alias PC(18:2/0:0), 1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC, 18:2/0:0-PC, 18:2 lyso-PC, 18:2 LysoPC

Lysophosphatidylcholine 18:2 is a mouse metabolite functionally related to linoleic acid.18:2 LysoPC is a major component of oxidized low-density lipoproteins (LDLs), and low plasma levels of LPC 18:2 have been associated with metabolic disorders such as impaired glucose tolerance, insulin resistance, type 2 diabetes, and coronary artery disease.1-Linoleoyl 1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC is also a substrate for the generation of lysophosphatidic acid (LPA) from Autotaxin (LysoPLD), which plays an important role in cell motility.

Lysophosphatidylcholine 18:2

Lysophosphatidylcholine 18:2

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Catalog No. T36791Alias PC(18:2/0:0), 1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC, 18:2/0:0-PC, 18:2 lyso-PC, 18:2 LysoPCCas No. 22252-07-9
Lysophosphatidylcholine 18:2 is a mouse metabolite functionally related to linoleic acid.18:2 LysoPC is a major component of oxidized low-density lipoproteins (LDLs), and low plasma levels of LPC 18:2 have been associated with metabolic disorders such as impaired glucose tolerance, insulin resistance, type 2 diabetes, and coronary artery disease.1-Linoleoyl 1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC is also a substrate for the generation of lysophosphatidic acid (LPA) from Autotaxin (LysoPLD), which plays an important role in cell motility.
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5 mgInquiry35 days
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Concentration:5.0 mg/mL
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Product Introduction

Bioactivity
Description
Lysophosphatidylcholine 18:2 is a mouse metabolite functionally related to linoleic acid.18:2 LysoPC is a major component of oxidized low-density lipoproteins (LDLs), and low plasma levels of LPC 18:2 have been associated with metabolic disorders such as impaired glucose tolerance, insulin resistance, type 2 diabetes, and coronary artery disease.1-Linoleoyl 1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC is also a substrate for the generation of lysophosphatidic acid (LPA) from Autotaxin (LysoPLD), which plays an important role in cell motility.
In vitro
Lysophosphatidylcholine 18:2 is a major glycerophospholipid in human plasma and has been implicated in inflammation, insulin resistance, obesity, and type 2 diabetes.[1]
AliasPC(18:2/0:0), 1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC, 18:2/0:0-PC, 18:2 lyso-PC, 18:2 LysoPC
Chemical Properties
Molecular Weight519.65
FormulaC26H50NO7P
Cas No.22252-07-9
SmilesCCCCC\C=C/C\C=C/CCCCCCCC(=O)OC[C@@H](O)COP([O-])(=O)OCC[N+](C)(C)C
Storage & Solubility Information
Storagestore under nitrogen | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
PBS (pH 7.2): 1.00 mg/mL (1.92 mM), Sonication is recommended.
Ethanol: 80.00 mg/mL (153.95 mM), Sonication is recommended.
Solution Preparation Table
PBS (pH 7.2)/Ethanol
1mg5mg10mg50mg
1 mM1.9244 mL9.6219 mL19.2437 mL96.2186 mL
Ethanol
1mg5mg10mg50mg
5 mM0.3849 mL1.9244 mL3.8487 mL19.2437 mL
10 mM0.1924 mL0.9622 mL1.9244 mL9.6219 mL
20 mM0.0962 mL0.4811 mL0.9622 mL4.8109 mL
50 mM0.0385 mL0.1924 mL0.3849 mL1.9244 mL
100 mM0.0192 mL0.0962 mL0.1924 mL0.9622 mL

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