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Lysophosphatidylcholine 18:2 is a mouse metabolite functionally related to linoleic acid.18:2 LysoPC is a major component of oxidized low-density lipoproteins (LDLs), and low plasma levels of LPC 18:2 have been associated with metabolic disorders such as impaired glucose tolerance, insulin resistance, type 2 diabetes, and coronary artery disease.1-Linoleoyl 1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC is also a substrate for the generation of lysophosphatidic acid (LPA) from Autotaxin (LysoPLD), which plays an important role in cell motility.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
500 μg | Inquiry | 35 days | |
1 mg | Inquiry | 35 days | |
5 mg | Inquiry | 35 days |
Description | Lysophosphatidylcholine 18:2 is a mouse metabolite functionally related to linoleic acid.18:2 LysoPC is a major component of oxidized low-density lipoproteins (LDLs), and low plasma levels of LPC 18:2 have been associated with metabolic disorders such as impaired glucose tolerance, insulin resistance, type 2 diabetes, and coronary artery disease.1-Linoleoyl 1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC is also a substrate for the generation of lysophosphatidic acid (LPA) from Autotaxin (LysoPLD), which plays an important role in cell motility. |
In vitro | Lysophosphatidylcholine 18:2 is a major glycerophospholipid in human plasma and has been implicated in inflammation, insulin resistance, obesity, and type 2 diabetes.[1] |
Alias | PC(18:2/0:0), 1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC, 18:2/0:0-PC, 18:2 lyso-PC, 18:2 LysoPC |
Molecular Weight | 519.65 |
Formula | C26H50NO7P |
Cas No. | 22252-07-9 |
Smiles | CCCCC\C=C/C\C=C/CCCCCCCC(=O)OC[C@@H](O)COP([O-])(=O)OCC[N+](C)(C)C |
Storage | store under nitrogen | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
Solubility Information | PBS (pH 7.2): 1.00 mg/mL (1.92 mM), Sonication is recommended. Ethanol: 80.00 mg/mL (153.95 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
PBS (pH 7.2)/Ethanol
Ethanol
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