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1-Oleoyl Lysophosphatidic Acid
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Catalog No. T36907Cas No. 65528-98-5
Alias Oleoyl-sn-3-Glycerophosphate, 1-Oleoyl LPA
1-Oleoyl Lysophosphatidic Acid (1-Oleoyl LPA) is a biologically active phospholipid that can exert multiple biological effects in various disease states of the kidney by activating a complex network of at least six homologous G protein-coupled receptors and their heterotrimeric G proteins. 1-Oleoyl Lysophosphatidic Acid promotes polarization of BV-2 and primary murine microglia toward an M1-like phenotype and can be used to study cancer and atherosclerosis.
1-Oleoyl Lysophosphatidic Acid
😃Good
Catalog No. T36907Alias Oleoyl-sn-3-Glycerophosphate, 1-Oleoyl LPACas No. 65528-98-5
1-Oleoyl Lysophosphatidic Acid (1-Oleoyl LPA) is a biologically active phospholipid that can exert multiple biological effects in various disease states of the kidney by activating a complex network of at least six homologous G protein-coupled receptors and their heterotrimeric G proteins. 1-Oleoyl Lysophosphatidic Acid promotes polarization of BV-2 and primary murine microglia toward an M1-like phenotype and can be used to study cancer and atherosclerosis.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg (22.91 mM * 100 μL in Ethanol) | $65 | 35 days | |
| 5 mg (22.91 mM * 500 μL in Ethanol) | $255 | 35 days | |
| 10 mg (22.91 mM * 1 mL in Ethanol) | $418 | 35 days | |
| 25 mg (22.91 mM * 2.5 mL in Ethanol) | $878 | 35 days |
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CitedSelect Batch
Concentration:10.0 mg/mL
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Product Introduction
Bioactivity
Chemical Properties
| Description | 1-Oleoyl Lysophosphatidic Acid (1-Oleoyl LPA) is a biologically active phospholipid that can exert multiple biological effects in various disease states of the kidney by activating a complex network of at least six homologous G protein-coupled receptors and their heterotrimeric G proteins. 1-Oleoyl Lysophosphatidic Acid promotes polarization of BV-2 and primary murine microglia toward an M1-like phenotype and can be used to study cancer and atherosclerosis. |
| In vivo | METHODS: 1-Oleoyl Lysophosphatidic Acid(0.4-2 μg, i.v. for 9 weeks) treated rats and behaviorally assessed. RESULTS: 1-Oleoyl Lysophosphatidic Acid induced anxiety-like responses in the elevated plus maze (EPM). [5] |
| Alias | Oleoyl-sn-3-Glycerophosphate, 1-Oleoyl LPA |
| Molecular Weight | 436.52 |
| Formula | C21H41O7P |
| Cas No. | 65528-98-5 |
| Smiles | O(C(CCCCCCC/C=C\CCCCCCCC)=O)C[C@H](COP(=O)(O)O)O |
| Relative Density. | 1.103 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||
| Solubility Information | Ethanol: 10 mg/mL（22.91 mM), Sonication is recommended. DMF: 1 mg/mL（2.29 mM), Sonication is recommended. DMSO: 1 mg/mL（2.29 mM), Sonication is recommended. PBS (pH 7.2): 1 mg/mL（2.29 mM), Sonication is recommended. | ||||||||||
Solution Preparation Table | |||||||||||
DMF/DMSO/PBS (pH 7.2)/Ethanol
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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