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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $57 | In Stock | |
5 mg | $145 | In Stock | |
10 mg | $216 | In Stock | |
25 mg | $366 | In Stock | |
50 mg | $548 | In Stock | |
100 mg | $762 | In Stock | |
200 mg | $995 | In Stock |
Description | CYM50308 is a high affinity agonist of sphingosine-1-phosphate receptor 4 (S1P4-R) (EC50: 56 nM). CYM50308 has no activity at S1P1-R, S1P2-R and S1P3-R subtypes at concentrations up to 25 μM and it shows 37-fold more selective for S1P4-R than S1P5-R. |
In vitro | CYM50308 shows low nanomolar S1P4-R agonist activity and exquisite selectivity over the other S1P-Rs subtypes. CYM50308 provides a valuable pharmacological tool to explore the effects of the S1P4-R signaling cascade and elucidate the molecular basis of the in vivo receptor function[1]. |
Molecular Weight | 405.46 |
Formula | C20H21F2N3O2S |
Cas No. | 1345858-76-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility Information | DMSO: 1 mg/ml ![]() |
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