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Product Introduction

Bioactivity

Description

10-Deacetylbaccatin-III is an intermediate for the preparation of taxol analogs, possessing anti-cancer activity.

Chemical Properties

Molecular Weight	544.59
Formula	C₂₉H₃₆O₁₀
Cas No.	32981-86-5

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 101 mg/mL (185.5 mM)

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

H2O: < 1 mg/mL (insoluble or slightly soluble)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.8362 mL	9.1812 mL	18.3624 mL	91.8122 mL
5 mM	0.3672 mL	1.8362 mL	3.6725 mL	18.3624 mL
10 mM	0.1836 mL	0.9181 mL	1.8362 mL	9.1812 mL
20 mM	0.0918 mL	0.4591 mL	0.9181 mL	4.5906 mL
50 mM	0.0367 mL	0.1836 mL	0.3672 mL	1.8362 mL
100 mM	0.0184 mL	0.0918 mL	0.1836 mL	0.9181 mL

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

10Deacetylbaccatin III10 Deacetylbaccatin III10-Deacetylbaccatin IIIinhibitInhibitor