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13(S)-HpODE
😃Good
Catalog No. T37393Cas No. 33964-75-9
13(S)-HpODE, a metabolite present in potato and Homo sapiens, is the (S)-enantiomer of 13-HpODE, a fatty acid containing a peroxy group, IL-13/13(S)HpODE stimulates MAO-A-mediated intracellular ROS generation and induction of p53 as well as p21 during apoptosis of A549 cancer cells and promotes apoptosis of HCT116 and CCF52 cells by upregulating p53 and p21 expression promoted apoptosis in HCT116 and CCF52 cells, constituting the IL-13 > 15-LO > 13(S)HpODE > PPARγ > MAO-A > ROS > p53 > p21 axis.
13(S)-HpODE
😃Good
Catalog No. T37393Cas No. 33964-75-9
13(S)-HpODE, a metabolite present in potato and Homo sapiens, is the (S)-enantiomer of 13-HpODE, a fatty acid containing a peroxy group, IL-13/13(S)HpODE stimulates MAO-A-mediated intracellular ROS generation and induction of p53 as well as p21 during apoptosis of A549 cancer cells and promotes apoptosis of HCT116 and CCF52 cells by upregulating p53 and p21 expression promoted apoptosis in HCT116 and CCF52 cells, constituting the IL-13 > 15-LO > 13(S)HpODE > PPARγ > MAO-A > ROS > p53 > p21 axis.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μg | $236 | 35 days | |
| 100 μg | Inquiry | 35 days | |
| 500 μg | Inquiry | 35 days | |
| 1 mg | Inquiry | 35 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | 13(S)-HpODE, a metabolite present in potato and Homo sapiens, is the (S)-enantiomer of 13-HpODE, a fatty acid containing a peroxy group, IL-13/13(S)HpODE stimulates MAO-A-mediated intracellular ROS generation and induction of p53 as well as p21 during apoptosis of A549 cancer cells and promotes apoptosis of HCT116 and CCF52 cells by upregulating p53 and p21 expression promoted apoptosis in HCT116 and CCF52 cells, constituting the IL-13 > 15-LO > 13(S)HpODE > PPARγ > MAO-A > ROS > p53 > p21 axis. |
| In vivo | Methods: Wild-type C57BL/6J mice were injected subcutaneously in the back with 200 μL of vehicle containing 0, 0.75, 1.5, 3, and 6 μg of 13(S)-HpODE per mouse. Results: 13(S)-HpODE administration dose-dependently reduced the anti-inflammatory properties of HDL in mice. [4] |
| Molecular Weight | 312.44 |
| Formula | C18H32O4 |
| Cas No. | 33964-75-9 |
| Smiles | [C@@H](/C=C/C=C\CCCCCCCC(O)=O)(CCCCC)OO |
Storage & Solubility Information
| Storage | store at low temperature | store at 4°C | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | PBS (pH 7.2): 1 mg/mL (3.2 mM), Sonication is recommended. DMSO: 10 mg/mL (32.01 mM), Sonication is recommended. Ethanol: 10 mg/mL (32.01 mM), Sonication is recommended. DMF: 10 mg/mL (32.01 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
PBS (pH 7.2)/DMSO/Ethanol/DMF
DMSO/Ethanol/DMF
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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