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2-Arachidonoylglycerol
🥰Excellent
Catalog No. T14011Cas No. 53847-30-6
2-Arachidonoylglycerol activates neuronal cannabinoid receptors as a full agonist, and prevents the induction of long-term potentiation at CA3–CA1 synapses.
2-Arachidonoylglycerol
🥰Excellent
Purity: 95% (as a 9:1 mixture of the 2-AG and 1-AG)
Catalog No. T14011Cas No. 53847-30-6
2-Arachidonoylglycerol activates neuronal cannabinoid receptors as a full agonist, and prevents the induction of long-term potentiation at CA3–CA1 synapses.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg (26.4 mM * 100 μL in Acetonitrile) | $118 | In Stock |
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Purity:95% (as a 9:1 mixture of the 2-AG and 1-AG)
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Product Introduction
Bioactivity
Chemical Properties
| Description | In the central nervous system, 2-Arachidonoylglycerol is a second endogenous cannabinoid ligand |
| Targets&IC50 | CB1:0.8 μM |
| In vitro | 2-Arachidonylglycerol (2-AG), a cannabinoid ligand obtained from intestinal tissue, functions as a full agonist in activating neuronal cannabinoid receptors. It impedes the development of long-term potentiation at CA3-CA1 synapses and, by binding to cannabinoid receptors, produces effects characteristic of cannabinoid drugs[1]. |
| Molecular Weight | 378.55 |
| Formula | C23H38O4 |
| Cas No. | 53847-30-6 |
| Smiles | O(C(CO)CO)C(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O |
| Relative Density. | 0.992 g/cm3 |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 10 mg/mL (26.41 mM) | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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