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5-Hydroxylansoprazole

5-Hydroxylansoprazole
5-Hydroxylansoprazole (AG1908) is an active metabolite of Lansoprazole, a gastric proton-pump inhibitor used to treat various peptic diseases. Lansoprazole is metabolized through CYP2C19, resulting in the formation of 5-Hydroxylansoprazole[1][2].
Catalog No. T14051Cas No. 131926-98-2
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Purity:99.00%
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5-Hydroxylansoprazole

Purity: 99.00%
Catalog No. T14051Alias AG-1908, AG1908, AG 1908Cas No. 131926-98-2

5-Hydroxylansoprazole (AG1908) is an active metabolite of Lansoprazole, a gastric proton-pump inhibitor used to treat various peptic diseases. Lansoprazole is metabolized through CYP2C19, resulting in the formation of 5-Hydroxylansoprazole[1][2].
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Product Introduction

Bioactivity
Description
5-Hydroxylansoprazole (AG1908) is an active metabolite of Lansoprazole, a gastric proton-pump inhibitor used to treat various peptic diseases. Lansoprazole is metabolized through CYP2C19, resulting in the formation of 5-Hydroxylansoprazole[1][2].
AliasAG-1908, AG1908, AG 1908
Chemical Properties
Molecular Weight385.36
FormulaC16H14F3N3O3S
Cas No.131926-98-2
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 120 mg/mL (311.40 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5950 mL12.9749 mL25.9498 mL129.7488 mL
5 mM0.5190 mL2.5950 mL5.1900 mL25.9498 mL
10 mM0.2595 mL1.2975 mL2.5950 mL12.9749 mL
20 mM0.1297 mL0.6487 mL1.2975 mL6.4874 mL
50 mM0.0519 mL0.2595 mL0.5190 mL2.5950 mL
100 mM0.0259 mL0.1297 mL0.2595 mL1.2975 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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