keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
740 Y-P(TFA)(1236188-16-1 free base) (740YPDGFR(TFA)) is a potent and cell-permeable activator of PI3K.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | Inquiry | $ 96.00 | |
5 mg | Inquiry | $ 264.00 | |
10 mg | Inquiry | $ 369.00 | |
25 mg | Inquiry | $ 620.00 | |
50 mg | Inquiry | $ 944.00 | |
100 mg | Inquiry | $ 1,415.00 |
Description | 740 Y-P(TFA)(1236188-16-1 free base) (740YPDGFR(TFA)) is a potent and cell-permeable activator of PI3K. |
In vitro |
740 Y-P is a synthetic biotinylated peptide. 740 Y-P stimulates mitogenesis at the lowest concentration tested (1 mg/mL). The peptide stimulates mitogenesis in both the presence and absence of serum (0.5%) and in the former instance, a maximal response observed at 50 mg/mL. 740Y-P peptide to stimulate mitogenesis is highly specific and not a general feature of a cell-permeable SH2 domain-binding peptide [1]. 740Y-P is as effective as a growth factor (FGF2) at promoting neuronal cell survival via the established PI 3-kinase-Akt survival cascade. Stimulation of neuronal cell survival by the PDGFR740Y-P peptide is dose-dependent and does not require insulin[2]. |
Synonyms | PDGFR 740Y-P(TFA), 740 Y-P(TFA), 740YPDGFR(TFA) |
Molecular Weight | 3384.73 |
Formula | C143H223F3N43O41PS3 |
CAS No. | TQ0003L |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
740 Y-P(TFA)(1236188-16-1 free base) TQ0003L PI3K/Akt/mTOR signaling PI3K PDGFR 740Y-P(TFA) 740 Y P(TFA)(1236188 16 1 free base) 740 Y-P(TFA) 740 YP(TFA)(1236188161 free base) 740YPDGFR(TFA) inhibitor inhibit