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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,670 | 6-8 weeks | |
50 mg | $2,180 | 6-8 weeks | |
100 mg | $2,800 | 6-8 weeks |
Description | BI-4924 is an inhibitor of phosphoglycerate dehydrogenase (PHGDH) (IC50=3 nM). It has excellent Microsomal and hepatocytic stability. Intracellular trapping of BI-4924 disrupts serine biosynthesis at 72 h ( IC50: 2200 nM). |
In vitro | BI-4924 is a highly potent co-factor nicotinamide adenine dinucleotide (NADH/NAD+)-competitive PHGDH inhibitor and it shows high selectivity against the majority of other dehydrogenase targets[1] |
Molecular Weight | 499.36 |
Formula | C21H20Cl2N2O6S |
Cas No. | 2244452-09-1 |
Storage | store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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