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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $34 | In Stock | |
2 mg | $48 | In Stock | |
5 mg | $80 | In Stock | |
10 mg | $147 | In Stock | |
25 mg | $269 | In Stock | |
50 mg | $455 | In Stock | |
100 mg | $690 | In Stock | |
1 mL x 10 mM (in DMSO) | $113 | In Stock |
Description | BT18 is a mimic with function similar to glial cell line-derived neurotrophic factor (GDNF). BT18 has an effect on RET receptor tyrosine kinase RetA and GDNF family receptor GFRα1 function. |
In vitro | BT18 (1-50 μM; 90 minutes) activates AKT in a dose-dependent manner in MG87RET cell lines. BT18 (50 μM; 1-90 minutes) activates AKT and ERK1/2 in time-dependently in MG87RET cell lines. BT18 (5-50 μM; 15 minutes) appears to phosphorylate RET in the concentration of 50 μM both in GFP-transfected and in GFRD1-transfected cells [1]. |
Molecular Weight | 637.64 |
Formula | C30H31F4N3O6S |
Cas No. | 924811-53-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 98 mg/mL (153.69 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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