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Cardamonin
Cardamonin (Cardamomin) is a chalcone isolated from Alpiniae katsumadai. It has anticancer, anti-inflammatory, antimicrobial, antioxidant and anti-diabetic activities. It can inhibit mTOR, NF-κB, Akt, STAT3, Wnt/β-catenin and COX-2, inhibit the growth of breast cancer, and can be used to study acute kidney injury and chronic renal fibrosis.
Catalog No. T66078Cas No. 18956-16-6
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Cardamonin
Catalog No. T66078Cas No. 18956-16-6
Cardamonin (Cardamomin) is a chalcone isolated from Alpiniae katsumadai. It has anticancer, anti-inflammatory, antimicrobial, antioxidant and anti-diabetic activities. It can inhibit mTOR, NF-κB, Akt, STAT3, Wnt/β-catenin and COX-2, inhibit the growth of breast cancer, and can be used to study acute kidney injury and chronic renal fibrosis.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $38 | In Stock | |
| 5 mg | $60 | In Stock | |
| 10 mg | $98 | In Stock | |
| 25 mg | $193 | In Stock | |
| 50 mg | $286 | In Stock | |
| 100 mg | $426 | In Stock | |
| 500 mg | $983 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Cardamonin (Cardamomin) is a chalcone isolated from Alpiniae katsumadai. It has anticancer, anti-inflammatory, antimicrobial, antioxidant and anti-diabetic activities. It can inhibit mTOR, NF-κB, Akt, STAT3, Wnt/β-catenin and COX-2, inhibit the growth of breast cancer, and can be used to study acute kidney injury and chronic renal fibrosis. |
| In vitro | The cell viabilities of H9C2 and HL-1 treated with different concentrations of Cardamonin (0, 1.5, 3.125, 6.25, 12.5, 25, 50 and 100 μM) for 24 h were not remarkably changed, suggesting that Cardamonin under the tested doses showed no significant cytotoxicity to cells. [1] |
| In vivo | The male C57BL/6 J mice (8 weeks old, 20–22 g). The Cardamonin treatment group (DOX + Cardamonin) was pretreated with Cardamonin (20, 40 or 80 mg/kg/day) by gavage, and mice were then intraperitoneal injected with DOX. Cardamonin does-dependently increased the body weight of mice challenged with DOX. We also found that the ratio of heart weight to body weight was markedly increased by DOX, which was, however, decreased by Cardamonin treatment in a dose-dependent manner. [1] |
| Alias | Cardamomin, Alpinetin chalcone |
| Molecular Weight | 270.28 |
| Formula | C16H14O4 |
| Cas No. | 18956-16-6 |
| Storage | keep away from moisture,keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 100 mg/mL (369.99 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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