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Ceronapril
🥰Excellent
Catalog No. T25226Cas No. 111223-26-8
Alias SQ-29852, SQ29852, SQ 29852, Ceronaprilum
Ceronapril (SQ 29852) is an orally active and potent angiotensin-converting enzyme (ACE) inhibitor (IC50 : 36 nM) for the study of dementia and hypertension.
Ceronapril
🥰Excellent
Purity: 97.94%
Catalog No. T25226Alias SQ-29852, SQ29852, SQ 29852, CeronaprilumCas No. 111223-26-8
Ceronapril (SQ 29852) is an orally active and potent angiotensin-converting enzyme (ACE) inhibitor (IC50 : 36 nM) for the study of dementia and hypertension.
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Purity:97.94%
ee:100%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Ceronapril (SQ 29852) is an orally active and potent angiotensin-converting enzyme (ACE) inhibitor (IC50 : 36 nM) for the study of dementia and hypertension. |
| In vivo | In male SD rats, Ceronapril (SQ 29852) inhibits ACE, with ED50 values of 0.063 μM/kg and 0.53 μM/kg for intravenous injection and oral administration, respectively [1]. Ceronapril (100 mg/kg; p.o.; single dose or twice daily for 3 days) blocks ACE in peripheral sites of rats [2].[1]. |
| Alias | SQ-29852, SQ29852, SQ 29852, Ceronaprilum |
| Molecular Weight | 440.47 |
| Formula | C21H33N2O6P |
| Cas No. | 111223-26-8 |
| Smiles | C([C@@H](OP(CCCCC1=CC=CC=C1)(=O)O)CCCCN)(=O)N2[C@H](C(O)=O)CCC2 |
| Relative Density. | 1.31g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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