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Cycloolivil

Catalog No. T3839 CAS 3064-05-9

Synonyms: Isoolivil

Cycloolivil is a natural polyphenolic compound with a significant radical scavenging activity present in olive trees. Cycloolivil has antioxidant activity, it may prevent thrombotic complications associated to platelet hyperaggregability and be the base

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Cycloolivil, CAS 3064-05-9

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Purity: 98%

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Description

In vitro

Cycloolivil reduced the ability of thrombin to stimulate platelet aggregation. Cycloolivil reduced thrombin-evoked Ca(2+) release and entry to a similar extent to hydroxytyrosol. This effect was greater in platelets from patients with type 2 diabetes mellitus than in controls. Thrombin-, thapsigargin- and 2,5-di-(tert-butyl)-1,4-hydroquinone (TBHQ)-evoked protein tyrosine phosphorylation, which is involved in Ca(2+) signalling and platelet aggregation, is inhibited by Cycloolivil. Cycloolivil is a natural oxygen radical scavenger that reduces thrombin-induced protein tyrosine phosphorylation, Ca(2+) signalling and platelet aggregation[1].

Synonyms	Isoolivil
Molecular Weight	376.4
Formula	C20H24O7
CAS No.	3064-05-9

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Zbidi H, et al. Olive tree wood phenolic compounds with human platelet antiaggregant properties. Blood Cells Mol Dis. 2009 May-Jun;42(3):279-85.

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Keywords

Cycloolivil 3064-05-9 其他氧化还原 Free radical scavengers Platelet aggregation Others Thrombin Platelets Aggregation Isoolivil Inhibitor Antioxidants inhibit inhibitor

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