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DL-Goitrin

DL-Goitrin is a potent antithyroid compound found naturally in crucifers. DL-Goitrin is responsible for the induction of glutathione S-transferases. DL-Goitrin is a moderate inhibitor of purified bovine adrenal dopamine beta-hydroxylase, leads to a depression of brain norepinephrine and to an elevation of heart and adrenal dopamine.

Catalog No. T2S1778Cas No. 13190-34-6

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Purity:99.94%

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COA HNMR HPLC

DL-Goitrin

Catalog No. T2S1778Cas No. 13190-34-6

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Pack Size	Price	Availability
5 mg	$59	In Stock
10 mg	$97	In Stock
25 mg	$163	In Stock
50 mg	$243	In Stock
100 mg	$359	In Stock
1 mL x 10 mM (in DMSO)	$54	In Stock

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Product Introduction

Bioactivity

Description	DL-Goitrin is a potent antithyroid compound found naturally in crucifers. DL-Goitrin is responsible for the induction of glutathione S-transferases. DL-Goitrin is a moderate inhibitor of purified bovine adrenal dopamine beta-hydroxylase, leads to a depression of brain norepinephrine and to an elevation of heart and adrenal dopamine.
Alias	Goitrin

Chemical Properties

Molecular Weight	129.18
Formula	C₅H₇NOS
Cas No.	13190-34-6

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 50 mg/mL (387.09 mM)

Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	7.7411 mL	38.7057 mL	77.4114 mL	387.0568 mL
5 mM	1.5482 mL	7.7411 mL	15.4823 mL	77.4114 mL
10 mM	0.7741 mL	3.8706 mL	7.7411 mL	38.7057 mL
20 mM	0.3871 mL	1.9353 mL	3.8706 mL	19.3528 mL
50 mM	0.1548 mL	0.7741 mL	1.5482 mL	7.7411 mL
100 mM	0.0774 mL	0.3871 mL	0.7741 mL	3.8706 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

DL-GoitrinDLGoitrinInhibitorDL Goitrininhibit