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DW14800

Catalog No. T11131 CAS 2243709-60-4

DW14800 is an inhibitor of PRMT5 (IC50 = 17 nM), enhances the transcription of HNF4α, and reduces the level of H4R3me2s.

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DW14800, CAS 2243709-60-4

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

DW14800 is an inhibitor of PRMT5 (IC50 = 17 nM), enhances the transcription of HNF4α, and reduces the level of H4R3me2s.

Molecular Weight	512.64
Formula	C31H36N4O3
CAS No.	2243709-60-4

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Zheng BN, et al. Targeting PRMT5 Activity Inhibits the Malignancy of Hepatocellular Carcinoma by Promoting the Transcription of HNF4α. Theranostics. 2019 Apr 13;9(9):2606-2617.

Related Products

Related compounds with same targets

CPI-360 MS0124 UNC 0631 PFI-2 PRMT5-IN-2 Tazemetostat trihydrochloride SMYD3-IN-1 SMYD2-IN-1

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

DW14800 2243709-60-4 表观遗传 Histone Methyltransferase DW-14800 Inhibitor inhibitor inhibit

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