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Hamaudol

Catalog No. TN1723Cas No. 735-46-6

Hamaudol, a chromone isolated from Saposhnikovia divaricata, exhibits analgesic and anti-inflammatory activities, demonstrating inhibitory effects on COX-1 and COX-2 with respective values of 0.30 and 0.57 mM.

Hamaudol

Hamaudol

Purity: 99.62%
Catalog No. TN1723Cas No. 735-46-6
Hamaudol, a chromone isolated from Saposhnikovia divaricata, exhibits analgesic and anti-inflammatory activities, demonstrating inhibitory effects on COX-1 and COX-2 with respective values of 0.30 and 0.57 mM.
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5 mg$238In Stock
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Purity:99.62%
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Product Introduction

Bioactivity
Description
Hamaudol, a chromone isolated from Saposhnikovia divaricata, exhibits analgesic and anti-inflammatory activities, demonstrating inhibitory effects on COX-1 and COX-2 with respective values of 0.30 and 0.57 mM.
Targets&IC50
COX-1:0.30 mM, COX-2:57 mM
In vitro
The CHCl3 extract of the root of Angelica japonica showed high inhibitory activity against human gastric adenocarcinoma (MK-1) cell growth. From this extract, a new furanocoumarin named japoangelone and four furanocoumarin ethers of falcarindiol, named japoangelols A-D, were isolated together with caffeic acid methyl ester, four polyacetylenic compounds (panaxynol, falcarindiol, 8-O-acetylfalcarindiol, and (9Z)-1,9-heptadecadiene-4,6-diyne-3,8,11-triol), eight coumarins (osthol, isoimperatorin, scopoletin, byakangelicin, xanthotoxin, bergapten, oxypeucedanin methanolate, and oxypeucedanin hydrate), and two chromones (3'-O-acetylHamaudol, and Hamaudol)[1]
Chemical Properties
Molecular Weight276.28
FormulaC15H16O5
Cas No.735-46-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: <10 mM
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.6195 mL18.0976 mL36.1952 mL180.9758 mL
5 mM0.7239 mL3.6195 mL7.2390 mL36.1952 mL
10 mM0.3620 mL1.8098 mL3.6195 mL18.0976 mL

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