store at low temperture,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Isoderrone shows inhibitory effects on α-glucosidase in vitro; it is a protein tyrosine phosphatase 1B (PTP1B) inhibitor, with IC50 value of 22.7 ± 1.7 uM, suggests that it may be a new drug for treatment of type 2 diabetes.
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1 mg | Inquiry | $ 769.00 |
Description | Isoderrone shows inhibitory effects on α-glucosidase in vitro; it is a protein tyrosine phosphatase 1B (PTP1B) inhibitor, with IC50 value of 22.7 ± 1.7 uM, suggests that it may be a new drug for treatment of type 2 diabetes. |
In vitro | METHODS AND RESULTS: Two new pyrrolidine alkaloids, ficushispimines A (1) and B (2), a new Ï-(dimethylamino)caprophenone alkaloid, ficushispimine C (3), and a new indolizidine alkaloid, ficushispidine (4), together with the known alkaloid 5 and 11 known isoprenylated flavonoids 6 - 16, were isolated from the twigs of Ficus hispida. Their structures were elucidated by spectroscopic methods. CONCLUSIONS: Isoderrone (8), 3'-(3-methylbut-2-en-1-yl)biochanin A (11), myrsininone A (12), ficusin A (13), and 4',5,7-trihydroxy-6-[(1R*,6R*)-3-methyl-6-(1-methylethenyl)cyclohex-2-en-1-yl]isoflavone (14) showed inhibitory effects on α-glucosidase in vitro. |
Molecular Weight | 336.34 |
Formula | C20H16O5 |
CAS No. | 121747-89-5 |
store at low temperture,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Isoderrone 121747-89-5 Proteases/Proteasome Tyrosinase inhibitor inhibit