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2-Ketoglutaric acid

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Catalog No. T5980Cas No. 328-50-7

2-Ketoglutaric acid is a key molecule in the tricarboxylic acid cycle,is also connected to glutamic acid and glutamine metabolisms through the transamination reactions.

2-Ketoglutaric acid

2-Ketoglutaric acid

🥰Excellent
Purity: 99.28%
Catalog No. T5980Cas No. 328-50-7
2-Ketoglutaric acid is a key molecule in the tricarboxylic acid cycle,is also connected to glutamic acid and glutamine metabolisms through the transamination reactions.
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1 g$42In Stock
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Purity:99.28%
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Product Introduction

Bioactivity
Description
2-Ketoglutaric acid is a key molecule in the tricarboxylic acid cycle,is also connected to glutamic acid and glutamine metabolisms through the transamination reactions.
Targets&IC50
Tyrosinase:15 mM (IC50)
Chemical Properties
Molecular Weight146.1
FormulaC5H6O5
Cas No.328-50-7
SmilesOC(=O)CCC(=O)C(O)=O
Relative Density.1.2821 g/cm3 (Estimated)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 3.5 mg/mL (24.10 mM)
H2O: 50 mg/mL (342.23 mM), Sonication is recommended.
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM6.8446 mL34.2231 mL68.4463 mL342.2313 mL
5 mM1.3689 mL6.8446 mL13.6893 mL68.4463 mL
10 mM0.6845 mL3.4223 mL6.8446 mL34.2231 mL
20 mM0.3422 mL1.7112 mL3.4223 mL17.1116 mL
H2O
1mg5mg10mg50mg
50 mM0.1369 mL0.6845 mL1.3689 mL6.8446 mL
100 mM0.0684 mL0.3422 mL0.6845 mL3.4223 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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