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Isogentisin
Isogentisin (BRN 0258402), a compound isolated from Gentianaceae, is a novel compound for the prevention of smoking-induced endothelial damage.Isogentisin exhibits inhibitory effects on monoamine oxidase.
Catalog No. T32208Cas No. 491-64-5
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Isogentisin
Catalog No. T32208Alias BRN-0258402, BRN0258402, BRN 0258402Cas No. 491-64-5
Isogentisin (BRN 0258402), a compound isolated from Gentianaceae, is a novel compound for the prevention of smoking-induced endothelial damage.Isogentisin exhibits inhibitory effects on monoamine oxidase.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $195 | Backorder | |
| 5 mg | $430 | Backorder | |
| 10 mg | $640 | Backorder | |
| 25 mg | $1,110 | Backorder | |
| 50 mg | $1,690 | Backorder | |
| 100 mg | $2,620 | Backorder |
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CitedProduct Introduction
Bioactivity
Chemical Properties
| Description | Isogentisin (BRN 0258402), a compound isolated from Gentianaceae, is a novel compound for the prevention of smoking-induced endothelial damage.Isogentisin exhibits inhibitory effects on monoamine oxidase. |
| In vitro | The G. lutea leaf extract exhibited moderate cytotoxic effects toward HeLa cells with an IC50 value of 41.1 microg/mL. Isogenisin was isolated and identified from G. lutea leaves, isogentisin exerted strong activity against HeLa cells, with IC50 values is 8.8 ± 0.9 μg/mL.[1] |
| Alias | BRN-0258402, BRN0258402, BRN 0258402 |
| Molecular Weight | 258.2262 |
| Formula | C14H10O5 |
| Cas No. | 491-64-5 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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