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Isogentisin

Catalog No. T32208Cas No. 491-64-5
Alias BRN-0258402, BRN0258402, BRN 0258402

Isogentisin (BRN 0258402), a compound isolated from Gentianaceae, is a novel compound for the prevention of smoking-induced endothelial damage.Isogentisin exhibits inhibitory effects on monoamine oxidase.

Isogentisin

Isogentisin

Catalog No. T32208Alias BRN-0258402, BRN0258402, BRN 0258402Cas No. 491-64-5
Isogentisin (BRN 0258402), a compound isolated from Gentianaceae, is a novel compound for the prevention of smoking-induced endothelial damage.Isogentisin exhibits inhibitory effects on monoamine oxidase.
Pack SizePriceAvailabilityQuantity
1 mg$195Backorder
5 mg$430Backorder
10 mg$640Backorder
25 mg$1,110Backorder
50 mg$1,690Backorder
100 mg$2,620Backorder
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Product Introduction

Bioactivity
Description
Isogentisin (BRN 0258402), a compound isolated from Gentianaceae, is a novel compound for the prevention of smoking-induced endothelial damage.Isogentisin exhibits inhibitory effects on monoamine oxidase.
In vitro
The G. lutea leaf extract exhibited moderate cytotoxic effects toward HeLa cells with an IC50 value of 41.1 microg/mL. Isogenisin was isolated and identified from G. lutea leaves, isogentisin exerted strong activity against HeLa cells, with IC50 values is 8.8 ± 0.9 μg/mL.[1]
AliasBRN-0258402, BRN0258402, BRN 0258402
Chemical Properties
Molecular Weight258.2262
FormulaC14H10O5
Cas No.491-64-5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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