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Allylthiourea

Allylthiourea
Allylthiourea (Thiosinamine), a metabolic inhibitor, specifically suppresses ammonia oxidation.
Catalog No. T0418Cas No. 109-57-9
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Purity:98.71%
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Allylthiourea

Catalog No. T0418Alias Thiosinamine, N-AllylthioureaCas No. 109-57-9

Allylthiourea (Thiosinamine), a metabolic inhibitor, specifically suppresses ammonia oxidation.
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Product Introduction

Bioactivity
Description
Allylthiourea (Thiosinamine), a metabolic inhibitor, specifically suppresses ammonia oxidation.
In vivo
At a concentration of 1 μM, allylthiourea inhibits 80% of ammonia oxidation; selective inhibition of ammonia oxidation occurs at concentrations ranging from 8-80 μM; at a concentration of 86 μM, allylthiourea achieves complete inhibition of ammonia oxidation.
AliasThiosinamine, N-Allylthiourea
Chemical Properties
Molecular Weight116.18
FormulaC4H8N2S
Cas No.109-57-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (473.4 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: 22 mg/mL (189.3 mM)
Solution Preparation Table
Ethanol/DMSO
1mg5mg10mg50mg
1 mM8.6073 mL43.0367 mL86.0733 mL430.3667 mL
5 mM1.7215 mL8.6073 mL17.2147 mL86.0733 mL
10 mM0.8607 mL4.3037 mL8.6073 mL43.0367 mL
20 mM0.4304 mL2.1518 mL4.3037 mL21.5183 mL
50 mM0.1721 mL0.8607 mL1.7215 mL8.6073 mL
100 mM0.0861 mL0.4304 mL0.8607 mL4.3037 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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2 Enter the in vivo formulation:
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