Shopping Cart
- Remove All
Your shopping cart is currently empty
Isolicoflavonol
Isolicoflavonol inhibits Human carboxylesterase 2 (hCES2A) which is a key target to ameliorate the intestinal toxicity triggered by irinotecan that causes severe diarrhea in 50%-80% of patients receiving this anticancer agent.
Catalog No. TN1783Cas No. 94805-83-1
Select Batch
Contact us for more batch information
Resource Download
Isolicoflavonol
Catalog No. TN1783Cas No. 94805-83-1
Isolicoflavonol inhibits Human carboxylesterase 2 (hCES2A) which is a key target to ameliorate the intestinal toxicity triggered by irinotecan that causes severe diarrhea in 50%-80% of patients receiving this anticancer agent.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $898 | Backorder |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "Isolicoflavonol"
Probucol
DH-581
T025423288-49-5
Probucol (DH-581), an anti-hyperlipidemic drug, can lower the level of cholesterol in the bloodstream by increasing the LDL catabolic rate.
- $58
Size
QTY
Dehydrocholate sodium
Sodium dehydrocholate
T0516145-41-5
Dehydrocholate sodium, a hydrocholeretic, can increase bile output to clear increased bile acid load.
- $35
Size
QTY
Fenipentol
Pancoral, 1-Phenylpentanol, 1-phenylpentan-1-ol, 1-Phenyl-1-pentanol
T0857583-03-9
Fenipentol (Pancoral) has the properties of Choleretics and Cholagogues.
- $29
Size
QTY
Ethyl phenylglyoxylate
AI3-10033, AI310033, AI3 10033
T203511603-79-8
Ethyl phenylglyoxylate (AI3 10033) is a simultaneous inhibitor and substrate of chicken liver carboxylesterase.
- $29
Size
QTY
MSU-42011
T774992456434-36-7In house
MSU-42011 is an orally active retinoid X receptor-like (RXR) agonist. It potently inhibits the expression of iNOS, low SREBP-induced and activated RXR, and p-ERK at the protein level. MSU-42011 has demonstrated antitumor activity in a [kras]-driven mouse model of lung cancer and is effective for the treatment of preclinical [kras]-driven lung cancer with immunomodulatory activity.
- $41
Size
QTY
Lifibrol
U-83860, U 83860, K-12148, K12148, K-12.148
T2783296609-16-4In house
Lifibrol (U-83860) is an inhibitor of cholesterol synthesis.Lifibrol has anticholesterol and hypolipidemic properties and promotes the conversion of LDL Apo B-100 in patients with hypercholesterolemia and mixed hyperlipidemia.
- $146
Size
QTY
Mevastatin
ML236B, Compactin
T068373573-88-3
Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum. Mevastatin was the first statin to enter clinical trials.
- $51
Size
QTY
Carboxylesterase-IN-3
T607882764748-92-5In house
Carboxylesterase-IN-3 is a potent inhibitor of Carboxylesterase Notum (IC50 ≤ 10 nM).Carboxylesterase-IN-3 has the potential to study cancer diseases.
- $93
Size
QTY
Betulin
Cited
Trochol, Betulol, betulinol, betulinic alcohol, betuline
T3121473-98-3
Betulin (betulinol) (lup-20(29)-ene-3β, 28-diol) is an abundant, naturally occurring triterpene. It is commonly isolated from the bark of birch trees where it forms up to 30% of the dry weight of the extractive and is found in birch sap as well.
- $50
Size
QTY
CitedCarboxylesterase-IN-2
T775242764748-88-9
Carboxylesterase-IN-2 is a potent Carboxylesterase Notum inhibitor (IC50 <= 10 nM).Carboxylesterase-IN-2 has potential for the study of cancer diseases.
- $93
Size
QTY
Product Introduction
Bioactivity
Chemical Properties
| Description | Isolicoflavonol is a potential cancer chemopreventive agent. |
| Targets&IC50 | CES2A (human):<1.0 μM(Ki) |
| Molecular Weight | 354.35 |
| Formula | C20H18O6 |
| Cas No. | 94805-83-1 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Isolicoflavonol | purchase Isolicoflavonol | Isolicoflavonol cost | order Isolicoflavonol | Isolicoflavonol chemical structure | Isolicoflavonol formula | Isolicoflavonol molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.