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Isoschaftoside

Catalog No. T3897   CAS 52012-29-0

Isoschaftoside is used as an intercrop due to its allelopathic inhibition of parasitism by Striga hermonthica, an obligate parasitic weed that can devastate the maize crop. Isoschaftoside has anti-tumor, antioxidant, and antimicrobial activities, it also possesses strong nematicidal activity against M. incognita.

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Isoschaftoside Chemical Structure
Isoschaftoside, CAS 52012-29-0
Pack Size Availability Price/USD Quantity
1 mg In stock $ 50.00
5 mg In stock $ 112.00
10 mg In stock $ 163.00
25 mg In stock $ 272.00
50 mg In stock $ 393.00
1 mL * 10 mM (in DMSO) In stock $ 170.00
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Purity: 99.96%
Purity: 99.57%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Isoschaftoside is used as an intercrop due to its allelopathic inhibition of parasitism by Striga hermonthica, an obligate parasitic weed that can devastate the maize crop. Isoschaftoside has anti-tumor, antioxidant, and antimicrobial activities, it also possesses strong nematicidal activity against M. incognita.
In vitro METHODS AND RESULTS:In East African small-holder farming of maize, the cattle forage legume, Desmodium uncinatum is used as an intercrop due to its allelopathic inhibition of parasitism by Striga hermonthica, an obligate parasitic weed that can devastate the maize crop. Bioassay-guided fractionation of the root extract of D. uncinatum revealed Isoschaftoside to be the main compound in the most potent fraction inhibiting growth of germinated S. hermonthica radicles. Bioassays repeated with Isoschaftoside isolated from a different plant source, Passiflora incarnata, proved it to be a biologically active component. CONCLUSIONS: Analysis of the root exudates produced by hydroponically grown D. uncinatum showed Isoschaftoside to be present in the hydroponic media at biologically active concentrations of 10-100 nM.
Source
Molecular Weight 564.49
Formula C26H28O14
CAS No. 52012-29-0

Storage

keep away from direct sunlight

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (88.58 mM)

TargetMolReferences and Literature

1. Isoschaftoside, a C-glycosylflavonoid from Desmodium uncinatum root exudate, is an allelochemical against the development of Striga. Phytochemistry, 2010, 71(8-9):904-908. 2. Phenol content related to antioxidant and antimicrobial activities of Passiflora spp. extracts. European Food Research and Technology, 2006, 223(1):102-109. 3. Nematocidal Flavone-C-Glycosides against the Root-Knot Nematode (Meloidogyne incognita) from Arisaema erubescens Tubers. Molecules, 2011, 16(6):5079-5086. 4. Network Pharmacology-based Study of the Active Constituents of Chinese Medicinal Formulae for Antitumor Mechanism. World Journal of Traditional Chinese Medicine (English), 2018.

Related compound libraries

This product is contained In the following compound libraries:
Antiparasitic Natural Product Library Anti-Cancer Active Compound Library Anti-Parasitic Compound Library Traditional Mongolian Medicine Compound Library Anti-Infection Compound Library Selected Plant-Sourced Compound Library Bioactive Compounds Library Max Polyphenolic Natural Product Library Bioactive Compound Library Traditional Chinese Medicine Monomer Library

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Keywords

Isoschaftoside 52012-29-0 Microbiology/Virology Anti-infection Antifungal Fungal inhibit Inhibitor inhibitor

 

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