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KB SRC 4
Catalog No. T11745Cas No. 1380088-03-8
KB SRC 4 is a selective and potent c-Src inhibitor with antitumour activity that inhibits the growth of cancer cells.
KB SRC 4
Catalog No. T11745Cas No. 1380088-03-8
KB SRC 4 is a selective and potent c-Src inhibitor with antitumour activity that inhibits the growth of cancer cells.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $149 | In Stock |
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Purity:99.66%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | KB SRC 4 is a selective and potent c-Src inhibitor with antitumour activity that inhibits the growth of cancer cells. |
| Targets&IC50 | c-Src:44 nM (Ki), c-Src:86 nM (Kd) |
| In vitro | KB SRC 4 is a highly selective c-Src inhibitor. The Kd for c-Src (86 nM) is consistent with the Ki obtained in our biochemical activity assay. Compound 4(KB SRC 4) exhibits selectivity among Src family members, with >2-fold selectivity over both Lck and Fgr, 8-fold selectivity over c-Yes, and >40-fold selectivity over Lyn, Hck, and Fyn.[1]. |
| Molecular Weight | 555.03 |
| Formula | C32H23ClN8 |
| Cas No. | 1380088-03-8 |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (144.14 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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