Powder: -20°C for 3 years | In solvent: -80°C for 1 year
KPT185 (KPT 185) is a selective CRM1 inhibitor, inducing apoptosis, cell-cycle arrest.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 48.00 | |
10 mg | Inquiry | $ 66.00 | |
25 mg | Inquiry | $ 107.00 | |
50 mg | Inquiry | $ 180.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | KPT185 (KPT 185) is a selective CRM1 inhibitor, inducing apoptosis, cell-cycle arrest. |
Targets&IC50 | CRM1:100-500nM |
Cell Research | Cells are seeded into 96-well plates and treated for 24, 48, and 72 hours with KPT-SINE at various concentrations ranging from 10 nM to 10 μM. Cell viability is evaluated using the cell proliferation reagent WST-1 according to the manufacturer's protocol. The absorbance of wells at 450 nm (reference wavelength, 650 nm) is measured with a microplate reader. (Only for Reference) |
Synonyms | KPT-185, KPT 185 |
Molecular Weight | 355.31 |
Formula | C16H16F3N3O3 |
CAS No. | 1333151-73-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: <1 mg/mL
DMSO: 66 mg/mL (185.8 mM)
Ethanol: 66 mg/mL (185.8 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
KPT185 1333151-73-7 Membrane transporter/Ion channel CRM1 KPT-185 KPT 185 inhibitor inhibit