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Leptomycin B (LMB) is a potent inhibitor of the nuclear export of proteins and is a potent antifungal antibiotic blocking the eukaryotic cell cycle. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | 202 € | In Stock | |
2 mg | 341 € | In Stock | |
5 mg | 619 € | In Stock | |
10 mg | 881 € | In Stock | |
25 mg | 1.320 € | In Stock | |
50 mg | 1.776 € | In Stock | |
100 mg | 2.403 € | In Stock | |
1 mL x 10 mM (in DMSO) | 282 € | In Stock |
Description | Leptomycin B (LMB) is a potent inhibitor of the nuclear export of proteins and is a potent antifungal antibiotic blocking the eukaryotic cell cycle. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue. |
Alias | LMB, CI 940 |
Molecular Weight | 540.73 |
Formula | C33H48O6 |
Cas No. | 87081-35-4 |
Smiles | CC\C(\C=C\[C@H]1OC(=O)C=C[C@@H]1C)=C\[C@H](C)C\C=C\C(\C)=C\[C@@H](C)C(=O)[C@@H](C)[C@H](O)[C@@H](C)C\C(C)=C\C(O)=O |
Relative Density. | 1.072 g/cm3 (Predicted) |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 70 mg/mL (129.45 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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