Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MC3482 is a specific inhibitor of sirtuin5 (SIRT5).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 213.00 | |
5 mg | In stock | $ 537.00 | |
10 mg | In stock | $ 775.00 | |
25 mg | In stock | $ 1,180.00 | |
50 mg | In stock | $ 1,590.00 | |
100 mg | In stock | $ 2,130.00 | |
500 mg | In stock | $ 4,280.00 |
Description | MC3482 is a specific inhibitor of sirtuin5 (SIRT5). |
In vitro | MC3482 selectively inhibits the desuccinylating activity of sirtuin5 (SIRT5) at a concentration of 50 μM, without altering SIRT5's intracellular expression levels. Both autophagy and mitophagy are enhanced in cells with silenced SIRT5 and in wild-type cells treated with MC3482, whereas these processes are diminished in cells overexpressing SIRT5[1]. |
Molecular Weight | 618.68 |
Formula | C33H38N4O8 |
CAS No. | T11962 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 117mg/mL (189.1mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
MC3482 T11962 Chromatin/Epigenetic DNA Damage/DNA Repair Sirtuin MC 3482 MC-3482 inhibitor inhibit