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Dihydrocoumarin (melilotin) is a compound found in Melilotus officinalis. Dihydrocoumarin is a yeast Sir2p inhibitor. Dihydrocoumarin also inhibits human SIRT1 and SIRT2 with IC50s of 208 μM and 295 μM, respectively.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 g | $29 | In Stock | |
1 mL x 10 mM (in DMSO) | $29 | In Stock |
Description | Dihydrocoumarin (melilotin) is a compound found in Melilotus officinalis. Dihydrocoumarin is a yeast Sir2p inhibitor. Dihydrocoumarin also inhibits human SIRT1 and SIRT2 with IC50s of 208 μM and 295 μM, respectively. |
Targets&IC50 | SIRT2 (human):295 μM, SIRT1 (human):208 μM |
Alias | melilotin, Hydrocoumarin, Chroman-2-one, 3,4-dihydrocoumarin, 2-chromanone |
Molecular Weight | 148.16 |
Formula | C9H8O2 |
Cas No. | 119-84-6 |
Smiles | O=C1CCC2=C(O1)C=CC=C2 |
Relative Density. | 1.169 g/cm3 at 25℃ (lit.) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 11 mg/mL (74.24 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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