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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $68 | In Stock | |
500 mg | $1,530 | In Stock |
Description | MC3482 is a specific inhibitor of sirtuin5 (SIRT5). |
In vitro | MC3482 selectively inhibits the desuccinylating activity of sirtuin5 (SIRT5) at a concentration of 50 μM, without altering SIRT5's intracellular expression levels. Both autophagy and mitophagy are enhanced in cells with silenced SIRT5 and in wild-type cells treated with MC3482, whereas these processes are diminished in cells overexpressing SIRT5[1]. |
Molecular Weight | 618.68 |
Formula | C33H38N4O8 |
Cas No. | 2922280-86-0 |
Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 117 mg/mL (189.1 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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