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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $30 | In Stock | |
5 mg | $68 | In Stock | |
10 mg | $103 | In Stock | |
25 mg | $193 | In Stock | |
50 mg | $257 | In Stock | |
100 mg | $343 | In Stock | |
200 mg | $492 | In Stock | |
1 mL x 10 mM (in DMSO) | $75 | In Stock |
Description | MLS0315771 is an effective and biologically active competitive phosphomannose isomerase (MPI) inhibitor (IC50: ~1 μM and a Ki: 1.4 μM). |
Targets&IC50 | MPI:1 μM (IC50) |
In vitro | MLS0315771 is toxic to the zebrafish embryos above 2 μM. MLS0315771 toxicity at higher concentrations is an off-target effect. MLS0315771 enhances mannose flux toward glycosylation. It ~50% of embryos appeared sick within 20 min at 8-10 μM, and most of them die by 30-60 min. |
Molecular Weight | 273.33 |
Formula | C15H12FNOS |
Cas No. | 727664-91-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 11 mg/mL (40.24 mM) | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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