Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Manassantin A is a high potent HIF-1 inhibitor, it protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effects might be associated with COX/PGE2 stimulation, inhibition of iNOS production and NF-κB activation, and improvements in the antioxidant and anti-inflammatory status.Manassantin A represents a potential therapeutic approach for the treatment of airway allergic-inflammatory diseases. Manassantin A inhibits cAMP-induced melanin production by down-regulating the gene expressions of MITF and tyrosinase in melanocytes.
Description | Manassantin A is a high potent HIF-1 inhibitor, it protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effects might be associated with COX/PGE2 stimulation, inhibition of iNOS production and NF-κB activation, and improvements in the antioxidant and anti-inflammatory status.Manassantin A represents a potential therapeutic approach for the treatment of airway allergic-inflammatory diseases. Manassantin A inhibits cAMP-induced melanin production by down-regulating the gene expressions of MITF and tyrosinase in melanocytes. |
Molecular Weight | 732.867 |
Formula | C42H52O11 |
CAS No. | 88497-87-4 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
( < 1 mg/ml refers to the product slightly soluble or insoluble )
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Manassantin A 88497-87-4 G蛋白偶联受体 JAK/STAT信号通路 MAPK信号通路 NF-Kb信号通路 表观遗传 凋亡 干细胞 免疫与炎症 神经科学 血管生成 ERK COX cAMP NF-κB HIF JNK MAPK STAT Prostaglandin Receptor TNF Inhibitor inhibitor inhibit