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Manassantin A

Catalog No. TN4489 CAS 88497-87-4

Manassantin A is a high potent HIF-1 inhibitor, it protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effects might be associated with COX/PGE2 stimulation, inhibition of iNOS production and NF-ÎºB activation, and improvements in the antioxidant and anti-inflammatory status.Manassantin A represents a potential therapeutic approach for the treatment of airway allergic-inflammatory diseases. Manassantin A inhibits cAMP-induced melanin production by down-regulating the gene expressions of MITF and tyrosinase in melanocytes.

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Manassantin A, CAS 88497-87-4

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Molecular Weight	732.867
Formula	C42H52O11
CAS No.	88497-87-4

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

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Keywords

Manassantin A 88497-87-4 G蛋白偶联受体 JAK/STAT信号通路 MAPK信号通路 NF-Kb信号通路表观遗传凋亡干细胞免疫与炎症神经科学血管生成 ERK COX cAMP NF-κB HIF JNK MAPK STAT Prostaglandin Receptor TNF Inhibitor inhibitor inhibit

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