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N-Acetyl-L-cysteine ethyl ester
Catalog No. T41285Cas No. 59587-09-6
Alias N-Acetylcysteine ethyl ester, NACET
N-Acetyl-L-cysteine ethyl ester (NACET) is a derivative of the amino acid L-cysteine. NACET has been shown to exhibit diverse biochemical and physiological effects, including inhibition of protein synthesis, inhibition of DNA replication, and induction of apoptosis. Additionally, it has demonstrated anti-inflammatory, antioxidant, and anti-cancer activity.
N-Acetyl-L-cysteine ethyl ester
Catalog No. T41285Alias N-Acetylcysteine ethyl ester, NACETCas No. 59587-09-6
N-Acetyl-L-cysteine ethyl ester (NACET) is a derivative of the amino acid L-cysteine. NACET has been shown to exhibit diverse biochemical and physiological effects, including inhibition of protein synthesis, inhibition of DNA replication, and induction of apoptosis. Additionally, it has demonstrated anti-inflammatory, antioxidant, and anti-cancer activity.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | $40 | In Stock | |
| 25 mg | $71 | In Stock | |
| 50 mg | $113 | In Stock | |
| 100 mg | $198 | In Stock | |
| 500 mg | $515 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $44 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | N-Acetyl-L-cysteine ethyl ester (NACET) is a derivative of the amino acid L-cysteine. NACET has been shown to exhibit diverse biochemical and physiological effects, including inhibition of protein synthesis, inhibition of DNA replication, and induction of apoptosis. Additionally, it has demonstrated anti-inflammatory, antioxidant, and anti-cancer activity. |
| In vitro | Under concomitant oxidative stress induced by 2 mM H2O2, N-Acetyl-L-cysteine ethyl ester (NACET) showed strong and significant protective effect on RPE cells when the concentration was 0.4 mM. Moreover, NACET treatment also resulted in an enhanced protective effect when RPE cells were stressed by the organic ROS generator peroxide tert-Butyl hydroperoxide (t-BOOH).NACET significantly increased both intracellular GSH and cysteine at 0.2 and 1 mM concentrations, respectively, as well as extracellular total GSH[2]. |
| Alias | N-Acetylcysteine ethyl ester, NACET |
| Molecular Weight | 191.25 |
| Formula | C7H13NO3S |
| Cas No. | 59587-09-6 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 45.0 mg/mL (235.3 mM), Sonication is recommended. H2O: 90.0 mg/mL (470.6 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO/H2O
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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