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N-Acetyl-L-cysteine ethyl ester (NACET) is a derivative of the amino acid L-cysteine. NACET has been shown to exhibit diverse biochemical and physiological effects, including inhibition of protein synthesis, inhibition of DNA replication, and induction of apoptosis. Additionally, it has demonstrated anti-inflammatory, antioxidant, and anti-cancer activity.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | $40 | In Stock | |
25 mg | $71 | In Stock | |
50 mg | $113 | In Stock | |
100 mg | $198 | In Stock | |
500 mg | $515 | In Stock | |
1 mL x 10 mM (in DMSO) | $44 | In Stock |
Description | N-Acetyl-L-cysteine ethyl ester (NACET) is a derivative of the amino acid L-cysteine. NACET has been shown to exhibit diverse biochemical and physiological effects, including inhibition of protein synthesis, inhibition of DNA replication, and induction of apoptosis. Additionally, it has demonstrated anti-inflammatory, antioxidant, and anti-cancer activity. |
In vitro | Under concomitant oxidative stress induced by 2 mM H2O2, N-Acetyl-L-cysteine ethyl ester (NACET) showed strong and significant protective effect on RPE cells when the concentration was 0.4 mM. Moreover, NACET treatment also resulted in an enhanced protective effect when RPE cells were stressed by the organic ROS generator peroxide tert-Butyl hydroperoxide (t-BOOH).NACET significantly increased both intracellular GSH and cysteine at 0.2 and 1 mM concentrations, respectively, as well as extracellular total GSH[2]. |
Alias | N-Acetylcysteine ethyl ester, NACET |
Molecular Weight | 191.25 |
Formula | C7H13NO3S |
Cas No. | 59587-09-6 |
Smiles | CCOC(=O)[C@H](CS)NC(C)=O |
Relative Density. | 1.138 g/cm3 (Predicted) |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 45.0 mg/mL (235.3 mM), Sonication is recommended. H2O: 90.0 mg/mL (470.6 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO/H2O
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