Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Nanchangmycin, a polyether antibiotic, is similar to the structure of dianemycin. It is very potent against the broad spectrum of harmful nematodes and insects but not for mammals and plants.
Description | Nanchangmycin, a polyether antibiotic, is similar to the structure of dianemycin. It is very potent against the broad spectrum of harmful nematodes and insects but not for mammals and plants. |
In vitro | Nanchangmycin resists gram-positive bacteria. |
In vivo | Nanchangmycin, a growth promoter in poultry, cures coccidiosis in chickens. Nanchangmycin, a bacterially-derived natural product, blocks ZIKV and DENV infection potently in diverse cell types. |
Kinase Assay | Histone deacetylase activity:For PCI-34051 characterization, measurements are performed in a reaction volume of 100 μL using 96-well assay plates in a fluorescence plate reader. For each isozyme. The HDAC protein in reaction buffer (50 mM HEPES, 100 mM KCl, 0.001% Tween-20, 5% dimethyl sulfoxide, pH7.4, supplemented with bovine serum albumin at concentrations of 0-0.05%) is mixed with PCI-34051 at various concentrations and allowed to incubate for 15 min. Trypsin is added to a final concentration of 50 nM, and acetyl-Gly-Ala-(N-acetyl-Lys)-amino-4-methyl coumarin is added to a final concentration of 25-100 μM to initiate the reaction. After a 30 min lag time, the fluorescence is measured over a 30 min time frame using an excitation wavelength of 335 nm and a detection wavelength of 460 nm. The increase in fluorescence with time is used as the measure of the reaction rate. |
Cell Research | 5×10E3 U2OS cells were plated in 25ul media per well in 384-well plates and cultured for 24 hours. Add 50 nl of Nanchangmycin, which is 0.7uM dissolved in 0.2% DMSO, to each well incubating for 1 hour. |
Synonyms | Nanchangmycin A |
Molecular Weight | 889.1 |
Formula | C48H80O13 |
CAS No. | 65101-87-3 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
H2O: <1 mg/mL
DMSO: 88.9 mg/mL (100 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Nanchangmycin 65101-87-3 Microbiology/Virology Antibacterial Antibiotic Inhibitor Nanchangmycin A inhibit Bacterial inhibitor